March 29

Study Reveals How Chinese Skullcap Makes Anti-Cancer Compounds

Richard Warren
Core Spirit member since Dec 24, 2020
Reading time less than 1 minute

A new study, published in the journal Science Advances, has revealed how the popular Chinese herbal remedy Huang-Qin (Scutellaria baicalensis) — also known as the Chinese skullcap — produces compounds which may help to treat cancer and liver diseases.

Chinese skullcap is cultivated in China, Siberia, Mongolia and Korea. It is an herb used in traditional Chinese medicine to treat a variety of conditions including epilepsy, hepatitis, infections, and cancer. It is often used in combination with other botanicals such as PC-SPES and sho-saiko-to.

Previous research on cells cultured in the lab has shown that certain compounds called flavones — found in the roots of the Chinese skullcap — not only have beneficial anti-viral and anti-oxidant effects, but they can also kill human cancer cells while leaving healthy cells untouched.

In live animal models, these flavones have also halted tumor growth, offering hope that they may one day lead to effective cancer treatments, or even cures.

As a group of compounds, the flavones are relatively well understood. But the beneficial flavones found in the roots of the Chinese skullcap — such as wogonin and baicalin — are different: a missing hydroxyl (-OH) group in their chemical structure left scientists scratching their heads as to how they were made in the plant.

“Many flavones are synthesized using a compound called naringenin as a building block,” said study senior author Prof. Cathie Martin, from the John Innes Centre in Norwich, UK.

“But naringenin has this -OH group attached to it, and there is no known enzyme that will remove it to produce the flavones we find in the Chinese skullcap roots.”

Prof. Cathie and her colleagues explored the possibility that Chinese skullcap’s root-specific flavones (RSFs) were made via a different biochemical pathway.

Step-by-step, they unraveled the mechanism involving new enzymes that make RSFs using a different building block called chrysin.

“We believe that this biosynthetic pathway has evolved relatively recently in Scutellaria roots, diverging from the classical pathway that produces flavones in leaves and flowers, specifically to produce chrysin and its derived flavones,” Prof. Martin said.

“Understanding the pathway should help us to produce these special flavones in large quantities, which will enable further research into their potential medicinal uses.”

“It’s exciting to consider that the plants which have been used as traditional Chinese remedies for thousands of years may lead to effective modern medicines,” she added.

by Sci News

Comments

Leave your questions here

To write a comment you must
or
Services
Category filter
Concern filter
Type filter
Sort
 
All categories
Art Therapy
$50 USD
Artist Teacher Workshop Or Tutoring

“Life Force” guiding our history, our body and spirits. Self portrait art, life drawing from the live model, gesture, and plein air painting. And extended cont…

Bryan Prillwitz
United States of America flag icon
Tarot Reading
$100 USD
Timeline Reading

EGYPTIAN TAROT READINGS using unique methods developed by Nelise Carbonare, a Brazilian healer with more than 40 years of experience in tarot consultations, as…

Nelise Carbonare
United States of America flag icon
Tarot Reading
$120 USD
THE SYNERGY OF THE PYRAMID

THE SYNERGY OF THE PYRAMID focuses on a specific relationship: One side for the consultant and one for their partner. (the partner does not need to be present …

Nelise Carbonare
United States of America flag icon
Tarot Reading
$10 USD
Pick one card

Many questions can be answer with just one Arcane.

Do you want to try?

Nelise Carbonare
United States of America flag icon
Personal Development Coaching
$50 USD
Spiritual Coaching - Removing Energy Blocks - Expansion

> “Who looks outside dreams. Who looks inside awakens.” Jung

Spiritual coaching is about moving you into a profound state of empowerment and involution m…

Kimla Rose (Kim Desrosiers)
United States of America flag icon
Life Coaching
$10 USD
Life Purpose and Soul Wisdom

What is your deeper truth, your deeper knowing, your MOJO, your deepest desires, those feelings that you can’t explain but that are so pure and so clear…or may…

Anna Beale
United States of America flag icon
Wellness Coaching
$10 USD
Your Missing Manual for Health & Life!

Are you constantly reading books, blogs and listening to podcasts trying to figure out what to do to be healthy?

With so much conflicting information out ther…

Pamela Malo
United States of America flag icon
Nutritional Therapy
$150 USD
Nutritional Therapy Consultation

Hi my name is Aria and I am the founder of Heal with Nutrition. I am a registered Nutritional Therapist and a Naturopath who has a passion on Nutrition and Hea…

Aria Alexandrou
United Kingdom of Great Britain and Northern Ireland flag icon
Tarot Reading
$10 USD
THOTH AND HERMETIC DECKS READING

With a deep knowledge of hermeticism and being introduced to the kabbalah tradition of the emanation process from the tree of life, I provide a deep insight co…

James Marchiori
Ireland flag icon
Personal Development Coaching
$55 USD
The Bridge to Your Desired Life

This is were you get real help with your struggles and life challenges. As life gets harder to cope with, we tend to look for external ways to get through. And…

Mina Mikhail
United States of America flag icon
Naturopathy
$10 USD
Intake Consult

short introduction consult to Integrative Medicine

Femke Neervoort
Netherlands flag icon
Career Coaching
$300 USD
Reset Coaching and Mentoring Programme

12 weeks of bi-weekly 90 minutes 1:1 Coaching and Mentoring. Total cost USD1800 (6x90minutes career coaching and mentoring session)

Are you returning to work …

Carla Martins
United Kingdom of Great Britain and Northern Ireland flag icon
Personal Development Coaching
$120 USD
Spiritual Life Coach Session-Personalized Session

Personalized Sessions

Because Everyone Is Unique

Client-centered sessions based on the area of focus requested by the client.

Each session is a LIVE Sessio…

Deborah Lucero
United States of America flag icon
Reiki
$55 USD
Guidance, Inspiration & Healing

This type of session is a favorite among many of my clients, as it is often times one of the smoothest way to address a challenge to reach a happier and health…

Mina Mikhail
United States of America flag icon
Mediumism
$10 USD
Psychic Readings

I specialize in love, past present future, future, past life, general, tarot, dream interpretation, specific, social, and career readings! Book today for clari…

Holly
United States of America flag icon
Life Coaching
$399 USD
1-on-1 Coaching

The journey started with our discovery call, and You decided: ” I’m ready! Let’s do this!”.

We will engage in 1-on-1 coaching sessions for 90 minutes. In this…

Carla Martins
United Kingdom of Great Britain and Northern Ireland flag icon
Ascension
$88 USD
Ascension Mentor Support

In this session, we come together with similar to a healing session but face to face.

We talk about what issues you are facing at the moment and we delve deep…

Claire C.
Australia flag icon
Spiritual Healing
$177 USD
Energy Healing

I am honored to assist you with intuitive channeled energy healings that support and nurture you on a physical level as well soul and energetic level, each ses…

Claire C.
Australia flag icon
Reiki
$375 USD
Usui Reiki 1st Degree Course

FIRST DEGREE COURSE - The ultimate Reiki course.

Have you ever wondered if you can heal? Have you felt a burning desire to help others? Then you’ve come to th…

Step Into Your Light - Christina Moore
United Kingdom of Great Britain and Northern Ireland flag icon
Life Coaching
$10 USD
Hand Analysis - Startup Session

What does a hand analysis do for me? ​

You will understand yourself and your life purpose. ​You will understand the roots of your triggers and reactionary be…

Brent Bruning, Master Hand Analyst
Switzerland flag icon
Shamanism
$10 USD
Sample Akashic Records Reading for Your Burning Issue

I connect to your Akashic Records and listen to what your guides want to bring to your conscoius attention at this time. Perhaps, it is an insight into why you…

Olga Aydınoğlu
Turkey flag icon
Shamanic Healing
$300 USD
Shamanic Healing Art

What is Shamanic Healing Art?

It is a physical artwork (usually a pastel drawing) I make for you based on the outcome of our online session. This artwork will…

Olga Aydınoğlu
Turkey flag icon
Shamanic Healing
$70 USD
Heal to say "No"

A limits and boundaries shamanic healing session to help you heal relevant wounds and traumas from this and/or other lifetimes, let go of false beliefs, judgem…

Olga Aydınoğlu
Turkey flag icon
Shamanic Healing
$70 USD
Writer's Block Shamanic Healing Session

Before the Session

I do my pre-meditation to find out the main reasons for your writer’s block. (This happens psychically, where I generally just need your na…

Olga Aydınoğlu
5
Turkey flag icon

Related Articles