Gut bacteria may reverse autism-related symptoms
Mar 29, 2018

Paula Montgomery
Core Spirit member since Dec 24, 2020
Reading time 2 min.

Scientists have identified a species of gut bacteria linked to behavioural deficits that may reverse symptoms of autism spectrum disorders.

The absence of the species of gut bacteria causes social deficits in mice, researchers at Baylor College of Medicine found.

By adding this bacteria species back to the guts of affected mice, the researchers were able to reverse some of their behavioural deficits, which are reminiscent of symptoms of autism spectrum disorders (ASDs) in humans.

“Other research groups are trying to use drugs or electrical brain stimulation as a way to reverse some of the behavioural symptoms associated with neurodevelopmental disorders - but here we have, perhaps, a new approach,” said Mauro Costa-Mattioli, a neuroscientist at Baylor College of Medicine in the US.

Previous studies in humans have found that maternal obesity during pregnancy ups children’s risk of developing neurodevelopmental disorders, including ASDs. Some people with ASD also report recurring gastrointestinal problems.

With emerging research showing how diet can change the gut microbiome and how gut microbes can influence the brain, researchers suspected there could be a connection.

They fed about 60 female mice a high-fat diet that was the rough equivalent of consistently eating fast food multiple times a day. They bred the mice daily.

The offspring stayed with their mother for three weeks and then were weaned onto a normal diet.

After a month, these offspring showed behavioural deficits, such as spending less time in contact with their peers and not initiating interactions.

“First we wanted to see if there was a difference in the microbiome between the offspring of mouse mothers fed a normal diet versus those of mothers fed a high-fat diet,” said Shelly Buffington, a postdoctoral fellow in Costa-Mattioli’s lab.

“We found a clear difference in the microbiota of the two maternal diet groups,” said Buffington.

Researchers then tested whether the specific differences in the microbiome were causative factors underlying the social impairments in offspring of mothers fed a high-fat diet.

Since the mice eat each other’s excrement, the researchers housed the animals together so that they would acquire microbiota from their cagemates.

When socially impaired three-week-old mice born to mothers on a high-fat diet were paired with normal mice, a full restoration of the gut microbiome and a concurrent improvement in behaviour was observed within four weeks.

The researchers concluded that one or more beneficial bacterial species might be important for normal social behaviour.

The researchers believe that their work, which uses a human bacteria species to promote oxytocin levels and improve social behavioural deficits in deficient mice, could be explored as a probiotic intervention for the treatment of neurodevelopmental disorders in humans. The study was published in the journal Cell.

by The Statesman

Leave your comments / questions for this practitioner

To write a comment please
Category filter
Concern filter
Type filter

All categories

Personality Psychology
$80 USD
therapy session
Individual Counselling Session (60 minutes)

I offer a compassionate counselling service that is unique to every woman and her situation. Allowing you to feel heard and understood in a safe environment free from shame and judgement.

My aim is to support and empower women through periods of change and emotionally difficult times. Empowering women to navigate their life and the mess that it can sometimes feel like it’s in with insight, respect, hope and strength.

I believe you have the desire and the capacity to grow towards fulfilling your true potential, and that you’re the expert on your own life. Counselling is a way of assisting you to identify and define your emotional issues and to help you better understand yourself.

Therefore, I don’t give advice. I will work with you to help you understand yourself more fully and to find your own inner resources. With greater self-awareness and trust in yourself, I hope that you will be able to make constructive changes, leading to a more satisfying and meaningful life.

I apply an integrated approach to counselling, meaning that I combine different but complementary counselling methods that have been taken from different models of therapy. These are Person-Centred Therapy, Cognitive Behaviour Therapy and Solution Focused Therapy. Using an integrative approach allows me to be flexible in providing a service that suits your situation.

I offer face-to-face and online individual counselling sessions, allowing women to openly talk about their emotional challenges.

Hayley Fualau
Personality Psychology
$150 USD
therapy session
Individual Psychotherapy

Are you seeking a therapist that sees you as a whole person - mind, body, and spirit, in the context of your lived experience and culture? Do you need someone to meet you where you are, without assumptions? Are you seeking help in your personal growth and healing?

All clinicians and support options are not the same. I am guided by a core philosophy that all human beings have an innate desire for balance, healing, and growth. Your definition of these concepts and your journey to achieve them is unique to you, your child, or your family.

Contact me to discuss scheduling.

Maybe you have specific complaints, stressors, or goals that you would like help navigating; perhaps you feel ready to strive for the next level of personal growth. Holistic Psychotherapy can offer the comprehensive tools and support you need to overcome personal challenges, interpersonal challenges, and to reach a healthier state of being. With the help and support of your therapist, you will be able to utilize your innate strengths to find yourself reaching the goals and understanding you seek in a safe and nonjudgmental space.

Stacey Wright
Personality Psychology
$750 USD
healing session

Finding it hard to get over that last relationship? Loving someone who is bad for you? These 4 hourly sessions will help place you into a mentally healthier place leaving behind the negative relationship and its lingering thoughts.

Jane Nash
Personality Psychology
$15 USD
therapy session

Facing difficulty in concentrating, relationships, academics, emotional concerns, stress etc. Counselling helps resolve these by aiding you with the necessary skills and cope up with these. Get in touch with our expert and professional counsellors/ psychologists.

Emotional well being helpline

Related Articles

View All
Personality Psychology
Feb 17 2021
This is how we get addicted

Love. We are all addicted to love indeed. Not just the idea, not just the feeling, but the neurochemistry of love. The experience of love favorably changes our neurophysiology in both mind and body. When we experience love, our body produces its own natur…

Demi Powell
Personality Psychology
Apr 16 2021
The Disappointing Double Standards of Narcissists

Disorders such as narcissism are characterized by a distortion of healthy norms for feeling, thinking and relating. One of the most notable distortions among narcissists is a pervasive set of double standards and paradoxes.

For example, people with narci…

Demi Powell
Personality Psychology
Mar 29 2018
A Groundbreaking New Discovery Explains How the Brain Creates Consciousness

Nobody yet understands how a collection of mushy cells in the brain gives rise to the brilliance of consciousness seen in higher-order animals, including humans. But two discoveries give scientists vital clues to how human consciousness works.

In 2014, a…

Felipe Thomas
Personality Psychology
Mar 29 2018
Seafood May Help Those At Risk of Alzheimer's

Seafood lovers, a new study delivers good news on two fronts: Mercury found in fish doesn’t lead to mental decline, and for certain people, a diet rich in fish might stave off Alzheimer’s disease.

Researchers who examined human brains confirmed that peop…

Paula Montgomery
Registered individuals enjoy all the possibilities of Core Spirit.