March 29

Gut bacteria can cause, predict and prevent rheumatoid arthritis

Tracy Campbell
Core Spirit member since Dec 24, 2020
Reading time 2 min.

The bacteria in your gut do more than break down your food. They also can predict susceptibility to rheumatoid arthritis, suggests Veena Taneja, Ph.D., an immunologist at Mayo Clinic’s Center for Individualized Medicine. Dr. Taneja recently published two studies – one in Genome Medicine and one in Arthritis and Rheumatology – connecting the dots between gut microbiota and rheumatoid arthritis.

More than 1.5 million Americans have rheumatoid arthritis, a disorder that causes painful swelling in the joints. Scientists have a limited understanding of the processes that trigger the disease. Dr. Taneja and her team identified intestinal bacteria as a possible cause; their studies indicate that testing for specific microbiota in the gut can help physicians predict and prevent the onset of rheumatoid arthritis.

“These are exciting discoveries that we may be able to use to personalize treatment for patients,” Dr. Taneja says.

The paper published in Genome Medicine summarizes a study of rheumatoid arthritis patients, their relatives and a healthy control group. The study aimed to find a biomarker – or a substance that indicates a disease, condition or phenomena – that predicts susceptibility to rheumatoid arthritis. They noted that an abundance of certain rare bacterial lineages causes a microbial imbalance that is found in rheumatoid arthritis patients.

“Using genomic sequencing technology, we were able to pin down some gut microbes that were normally rare and of low abundance in healthy individuals, but expanded in patients with rheumatoid arthritis,” Dr. Taneja says.

Implications for predicting and preventing rheumatoid arthritis

After further research in mice and, eventually, humans, intestinal microbiota and metabolic signatures could help scientists build a predictive profile for who is likely to develop rheumatoid arthritis and the course the disease will take, Dr. Taneja says.

Based on mouse studies, researchers found an association between the gut microbe Collinsella and the arthritis phenotype. The presence of these bacteria may lead to new ways to diagnose patients and to reduce the imbalance that causes rheumatoid arthritis before or in its early stages, according to John Davis III, M.D., and Eric Matteson, M.D., Mayo Clinic rheumatologists and study co-authors. Continued research could lead to preventive treatments.

Possibility for more effective treatment with fewer side effects

The second paper, published in Arthritis and Rheumatology, explored another facet of gut bacteria. Dr. Taneja treated one group of arthritis-susceptible mice with a bacterium, Prevotella histicola, and compared that to a group that had no treatment. The study found that mice treated with the bacterium had decreased symptom frequency and severity, and fewer inflammatory conditions associated with rheumatoid arthritis. The treatment produced fewer side effects, such as weight gain and villous atrophy – a condition that prevents the gut from absorbing nutrients – that may be linked with other, more traditional treatments.

While human trials have not yet taken place, the mice’s immune systems and arthritis mimic humans, and shows promise for similar, positive effects. Since this bacterium is a part of healthy human gut, treatment is less likely to have side effects, says study co-author Joseph Murray, M.D., a Mayo Clinic gastroenterologist.

Rheumatoid arthritis is an autoimmune disorder; it occurs when the body mistakenly attacks itself. The body breaks down tissues around joints, causing swelling that can erode bone and deform the joints. The disease can damage other parts of the body, including the skin, eyes, heart, lung and blood vessels.

by Science Daily

Comments

Leave your questions here

To write a comment you must
or
Services
Category filter
Concern filter
Type filter
Sort
 
All categories
Shamanic Healing
$10 USD
Light the Path to Your Desired Life

If you want find what is that in life that makes you happy and fulfilled you need to heal all levels of your existence- Body, Mind, and Spirit. We are all ener…

Change Naturopathy
New Zealand flag icon
Emotional Freedom Technique
$10 USD
The Power Of Emotional Healing - EFT Program

“The Power of Emotional Healing” is energy psychology education in the Emotional Freedom Technique with the perfect balance of information, instructions, video…

Dawn Cady
Australia flag icon
Spiritual Healing
$20 USD
Compassionate energy healing

For those times when we feel we need the energetic space to let our whole being restore itself. The healing is meant to give you a sense of safety and feel lik…

Nanna
Sweden flag icon
Art Therapy
$50 USD
Artist Teacher Workshop Or Tutoring

“Life Force” guiding our history, our body and spirits. Self portrait art, life drawing from the live model, gesture, and plein air painting. And extended cont…

Bryan Prillwitz
United States of America flag icon
Tarot Reading
$100 USD
Timeline Reading

EGYPTIAN TAROT READINGS using unique methods developed by Nelise Carbonare, a Brazilian healer with more than 40 years of experience in tarot consultations, as…

Nelise Carbonare
United States of America flag icon
Tarot Reading
$120 USD
THE SYNERGY OF THE PYRAMID

THE SYNERGY OF THE PYRAMID focuses on a specific relationship: One side for the consultant and one for their partner. (the partner does not need to be present …

Nelise Carbonare
United States of America flag icon
Tarot Reading
$10 USD
Pick one card

Many questions can be answer with just one Arcane.

Do you want to try?

Nelise Carbonare
United States of America flag icon
Personal Development Coaching
$50 USD
Spiritual Coaching - Removing Energy Blocks - Expansion

> “Who looks outside dreams. Who looks inside awakens.” Jung

Spiritual coaching is about moving you into a profound state of empowerment and involution m…

Kimla Rose (Kim Desrosiers)
United States of America flag icon
Life Coaching
$10 USD
Life Purpose and Soul Wisdom

What is your deeper truth, your deeper knowing, your MOJO, your deepest desires, those feelings that you can’t explain but that are so pure and so clear…or may…

Anna Beale
United States of America flag icon
Wellness Coaching
$10 USD
Your Missing Manual for Health & Life!

Are you constantly reading books, blogs and listening to podcasts trying to figure out what to do to be healthy?

With so much conflicting information out ther…

Pamela Malo
United States of America flag icon
Nutritional Therapy
$150 USD
Nutritional Therapy Consultation

Hi my name is Aria and I am the founder of Heal with Nutrition. I am a registered Nutritional Therapist and a Naturopath who has a passion on Nutrition and Hea…

Aria Alexandrou
United Kingdom of Great Britain and Northern Ireland flag icon
Tarot Reading
$10 USD
THOTH AND HERMETIC DECKS READING

With a deep knowledge of hermeticism and being introduced to the kabbalah tradition of the emanation process from the tree of life, I provide a deep insight co…

James Marchiori
Ireland flag icon
Personal Development Coaching
$55 USD
The Bridge to Your Desired Life

This is were you get real help with your struggles and life challenges. As life gets harder to cope with, we tend to look for external ways to get through. And…

Mina Mikhail
United States of America flag icon
Naturopathy
$10 USD
Intake Consult

short introduction consult to Integrative Medicine

Femke Neervoort
Netherlands flag icon
Career Coaching
$300 USD
Reset Coaching and Mentoring Programme

12 weeks of bi-weekly 90 minutes 1:1 Coaching and Mentoring. Total cost USD1800 (6x90minutes career coaching and mentoring session)

Are you returning to work …

Carla Martins
United Kingdom of Great Britain and Northern Ireland flag icon
Personal Development Coaching
$120 USD
Spiritual Life Coach Session-Personalized Session

Personalized Sessions

Because Everyone Is Unique

Client-centered sessions based on the area of focus requested by the client.

Each session is a LIVE Sessio…

Deborah Lucero
United States of America flag icon
Reiki
$55 USD
Guidance, Inspiration & Healing

This type of session is a favorite among many of my clients, as it is often times one of the smoothest way to address a challenge to reach a happier and health…

Mina Mikhail
United States of America flag icon
Mediumism
$10 USD
Psychic Readings

I specialize in love, past present future, future, past life, general, tarot, dream interpretation, specific, social, and career readings! Book today for clari…

Holly
United States of America flag icon
Life Coaching
$399 USD
1-on-1 Coaching

The journey started with our discovery call, and You decided: ” I’m ready! Let’s do this!”.

We will engage in 1-on-1 coaching sessions for 90 minutes. In this…

Carla Martins
United Kingdom of Great Britain and Northern Ireland flag icon
Ascension
$88 USD
Ascension Mentor Support

In this session, we come together with similar to a healing session but face to face.

We talk about what issues you are facing at the moment and we delve deep…

Claire C.
Australia flag icon
Spiritual Healing
$177 USD
Energy Healing

I am honored to assist you with intuitive channeled energy healings that support and nurture you on a physical level as well soul and energetic level, each ses…

Claire C.
Australia flag icon
Reiki
$375 USD
Usui Reiki 1st Degree Course

FIRST DEGREE COURSE - The ultimate Reiki course.

Have you ever wondered if you can heal? Have you felt a burning desire to help others? Then you’ve come to th…

Step Into Your Light - Christina Moore
United Kingdom of Great Britain and Northern Ireland flag icon
Life Coaching
$10 USD
Hand Analysis - Startup Session

What does a hand analysis do for me? ​

You will understand yourself and your life purpose. ​You will understand the roots of your triggers and reactionary be…

Brent Bruning, Master Hand Analyst
Switzerland flag icon
Shamanism
$10 USD
Sample Akashic Records Reading for Your Burning Issue

I connect to your Akashic Records and listen to what your guides want to bring to your conscoius attention at this time. Perhaps, it is an insight into why you…

Olga Aydınoğlu
Turkey flag icon

Related Articles